Phorbol 13-butanoate
WebJul 1, 2002 · The histone deacetylase inhibitor sodium butyrate interacts synergistically with phorbol myristate acetate (PMA) to induce mitochondrial damage and apoptosis in human myeloid leukemia cells through a tumor necrosis factor-alpha-mediated process WebThe enzyme phorbol-diester hydrolase (EC 3.1.1.51) catalyzes the reaction phorbol 12,13-dibutanoate + H 2 O phorbol 13-butanoate + butanoate. This enzyme belongs to the …
Phorbol 13-butanoate
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WebMar 1, 2004 · Therefore, the present studies were undertaken to examine whether hydrocortisone and phorbol 12-myristate 13-acetate (PMA) are involved in a possible regulation of the butyrate/anion exchange ... WebApr 23, 2024 · phorbol 12,13-dibutanoate + H 2 O → butanoate + phorbol 13-butanoate + H + Summary: Hydrolyses the 12-ester bond in a variety of 12,13-diacylphorbols (phorbol is a diterpenoid); this reaction inactivates the tumour promotor 12-O-tetradecanoylphorbol-13-acetate from croton oil.
WebSYMPTOMS: This material may cause skin irritation. ACUTE/CHRONIC HAZARDS: This compound may cause irritation upon contact with skin. (NTP, 1992) Reactivity Profile This material may be sensitive to prolonged exposure to air, light and ambient temperatures. It may also be subject to autooxidation. (NTP, 1992)
WebEC: 3.1.1.51 : Accepted name: phorbol-diester hydrolase: Reaction: phorbol 12,13-dibutanoate + H 2 O = phorbol 13-butanoate + butanoate: For diagram of reaction, click here Other name(s): diacylphorbate 12-hydrolase; diacylphorbate 12-hydrolase; phorbol-12,13-diester 12-ester hydrolase; PDEH Webphorbol 12,13-dibutanoate: ChEBI ID CHEBI:17598: Stars This entity has been manually annotated by the ChEBI Team. Secondary ChEBI IDs CHEBI:8117, CHEBI:14789, …
WebThe precursor protected in the 20-hydroxyl group of phorbol was acylated by [1-11 C]propyl ketene to the 13-hydroxyl group producing phorbol 13-[11 C]butyrate ([11 C]P13Bu). Total synthesis time was about 60 minutes and the specific activity was greater than 67 GBq/μmol (1800 mCi/μmol).
WebC03019 Phorbol 13-butanoate. BRITE hierarchy: Other DBs: PubChem: 5925: ChEBI: 17727: ChEMBL: CHEMBL3586005: NIKKAJI: J366.990D: KCF data: Show. ATOM 31 ... 18 13 19 2 … greenacres 4x4 warsopWebJul 1, 2002 · Interactions between the histone deacetylase inhibitor sodium butyrate (SB) and phorbol 12-myristate 13-acetate (PMA) were examined in human myeloid leukemia cells (U937 and HL-60). Exposure of U937 cells to 1 mM SB and 1 nM PMA (24 h) markedly induced caspase activation and apoptosis, events accompanied by impaired … flowering ornamental grass imagesWebPhorbol 12,13-dibutyrate C28H40O8 CID 37783 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological ... flowering orchid vanilla beanWeb(NTP, 1992) Health Hazard SYMPTOMS: This material may cause skin irritation. ACUTE/CHRONIC HAZARDS: This compound may cause irritation upon contact with skin. … flowering over in truro in odd placesWeb姜酮缓解葡聚糖硫酸钠盐诱导小鼠结肠炎的作用机制研究. 李敬, 罗娅, 张晟伟, 王静, 胡长江, 杨仕明. [ 摘要] 目的 探究姜酮 (zingerone, Zin)对葡聚糖硫酸钠盐 (dextran sodium sulfate,DSS)诱导小鼠结肠炎的治疗作用及其潜在免疫调节机制。. 方法 将SPF级6~8周龄C57BL/6雄性 ... flowering ornamental trees for landscapingWebWe studied the ability of inducers and inhibitors of erythroid differentiation of K562 leukemia cells, such as sodium butyrate, dimethyl sulfoxide, and phorbol-12-myristate-13-acetate, respectively, to modulate sensitivity of these cells to nonspecific lysis (nonrestricted with respect to antigens of the major histocompatibilty complex) mediated by natural human … flowering ornamental trees for zone 6ahttp://aammt.tmmu.edu.cn/html/202412057.htm green acres66 maison plein pied pmr