Webb13 sep. 2024 · We also tested that Phillyrin 50, 100 and 200µg/ml protected the cellular viability against the effect of ethanol by MTT assay, suggesting the potential efficacy of Phillyrin(Supplementary Fig. 2B). Here, all the results came to such a conclusion that Phillyrin targets PDPK1 to inhibit phosphorylation of PDPK1(Ser241). Webb7 sep. 2024 · Phillyrin (KD-1), a representative ingredient of Forsythia suspensa, possesses anti-inflammatory, anti-oxidant, and antiviral activities. However, little is known about the antiviral abilities and Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has extensively and rapidly spread in the world, causing an outbreak of acute …
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WebbPhillyrin (KD-1) exerts anti-viral and anti-inflammatory activities against novel coronavirus (SARS-CoV-2) and human coronavirus 229E (HCoV-229E) by suppressing the nuclear … Webb13 sep. 2024 · 3） Papers regarding COVID-19 research in which the cell lines we have provided were used. BRC Resource. Reference. 1. RCB2202 293T. Proc Natl Acad Sci U S A. 2008 Jun 3;105 (22):7809-14. Modulation of TNF-α-converting enzyme by the spike protein of SARS-CoV and ACE2 induces TNF-α production and facilitates viral entry. 2. simple respiratory system
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Webb1 aug. 2024 · Phillyrin (KD-1) exerts anti-viral and anti-inflammatory activities against novel coronavirus (SARS-CoV-2) and human coronavirus 229E (HCoV-229E) by suppressing … Webb30 mars 2024 · The present invention provides a use of a phillyrin/phillygenin composition which targets and inhibits 3CLpro protein of COVID-19 virus, in preparation of an anti-coronavirus drug or a drug for treating a disease caused by the coronavirus, wherein the coronavirus is COVID-19 virus, and the disease caused by the coronavirus is COVID-19. WebbMonteverdia aquifolia leaves extracts was obtained using pressurized-liquid extraction (PLE) and ultrasound-assisted extraction (UAE), evaluating, when pertinent, temperature, solvent, solvent/biomass ratio, and sonication amplitude (%), comparing to the conventional Soxhlet extraction (SOX) concerning yield (wt%), total phenolic content … simple responsive footer