Prolactin secretion is regulated by both stimulatory and inhibitory mechanisms. Dopamine acts on pituitary lactotroph D2 receptors to inhibit prolactin secretion while other peptides and hormones, such as thyrotropin releasing hormone (TRH), stimulate prolactin secretion. As a result, hyperprolactinemia may be caused by disinhibition (e.g., compression of the pituitary stalk or reduced dopamine levels) or excess production. The most common cause of hyperprolactinemi… Web1 aug. 2005 · Medication use is a common cause of hyperprolactinemia, and it is important to differentiate this cause from pathologic causes, such as prolactinomas.To ascertain the frequency of this clinical problem and to develop treatment guidelines, the medical literature was searched by using PubMed and the reference lists of other …
Hyperprolactinaemia: A guide for psychiatrists
Web6 jan. 2024 · Similarly, dopamine antagonists (such as the antipsychotics haloperidol and chlorpromazine) as well as a long list of other drugs — including selective serotonin reuptake inhibitors (SSRI), monoamine oxidase inhibitors (MAO-I) and some tricyclic antidepressants (TCA) — can cause hyperprolactinemia 1. Prolactin secretion. ... Web29 aug. 2024 · Other drugs known to cause hyperprolactinemia include clomipramine, metoclopramide, and certain opioids like methadone and morphine. Interestingly, opioids … phosphate formula charge
Hyperprolactinemia - StatPearls - NCBI Bookshelf
WebPhysiological causes of hyperprolactinaemia include pregnancy, lactation, stress, sexual inter course and sleep. There are a large number of pathological causes, including prolactinoma (usually associated with extremely elevated prolactin levels), chronic renal failure, liver cirrhosis, trauma and seizures. Non-functioning pituitary tumours can ... WebHyperprolactinemia without an identified cause requires imaging of the hypothalamic-pituitary area. A mildly elevated serum prolactin level may be due to a nonfunctioning pituitary adenoma or craniopharyngioma compressing the pituitary stalk, but high prolactin levels are commonly associated with a prolactin secreting prolactinoma.[ 1 ] Web25 jul. 2024 · Physiological, pathological, or pharmacological conditions can cause hyperprolactinemia. Any condition that affects secretion and clearance of prolactin will … phosphate free laundry detergent australia