WebSubchronic Oral Toxicity in Dogs. Chlorfenapyr was administered to dogs for 13 weeks at doses of 0, 60, 120 or 247 ppm (0, 2.16, 4.23 or 6.1 mg/kg/day, respectively). The LOAEL is 6.1 mg/kg/day (247 ppm), based on reduced body weight gain and feed efficiency and emaciation. The NOAEL is 4.23 mg/kg/day (120 ppm). WebFomesafen Sodium Salt 108731-70-0 22.1% 2. HAZARDS IDENTIFICATION Warning Classifications: ... Chronic/Subchronic Toxicity Studies Carcinogenicity Toxicity of …
5.14 GLYPHOSATE (158) AND METABOLITES TOXICOLOGY
WebES.3 SUBCHRONIC ORAL REFERENCE DOSE (RFD) FOR NONCANCER EFFECTS In addition to providing RfDs for chronic oral exposures in multiple systems, a less-than-lifetime subchronic RfD was derived for PFHxA. The same study and endpoint (Loveless et al., 2009) and decreased F 1 body weight and value was selected as the basis for the … Webthe NOAEL of 6.3 mg/kg bw/day from the rabbit developmental toxicity study. Due to the severe art of effects seen both in the rat and rabbit an additional safety factor of 3 was added. The ADI is 0.021 mg/kg bw/day. The AOEL is 0.0021 mg/kg bw/day since a correction for 10% oral absorption (based on available data) is required. mckinley byxor herr
Acute and Subchronic Toxicities and Safety Pharmacology
WebMay 3, 2006 · Table 1.—Subchronic, Chronic, and Other Toxicity. Guideline No. Study Type Results; 870.3050: 28-Day oral toxicity -- rodents (mouse) ... The fomesafen toxicity database is adequate for the risk assessment since we are not asking for a repeat developmental toxicity study in rabbits at this time. In addition, there is no evidence of … WebFomesafen is not acutely toxic to humans, avian species, freshwater fish and invertebrates, honey bees or marine species. The pesti- cide is slightly toxic to marine invertebrates. A … WebFomesafen - 1 . Web Publication Date: August 2024 . Toxicological Summary for: Fomesafen CAS ... Subchronic Noncancer Health- Based Value (nHBV Subchronic) = nHBV Short-term = 200 ... Source of toxicity value: Determined by MDH in 2024 . Point … mckinley buty trekkingowe