WebMicroRNAs (miRNAs) are linear single-stranded non-coding RNAs oligonucleotides, widely distributed in cells, playing a key role as regulators of gene expression at post … WebApr 12, 2024 · Recently, it has been reported that circRNA-protein interactions may play a role in the progression of various cancers . Thus, we performed RNA pull-down and mass spectrometry (MS) analysis to ...
Identification of Enzalutamide Resistance-Related circRNA-miRNA …
WebJan 15, 2024 · The circRNA-ACAP2 interaction regulated the expression of miR-21-5p, and miR-21-5p regulated the expression of Tiam1. ... *P< 0.01. (G) Relative protein expression of Tiam1 when circRNA-ACAP2 expression was knocked down. Each bar represents the mean of three independent experiments. *P< 0.05. (H) Relative protein … WebCircRNA as a Protein Sponge. In addition to being a miRNA sponge, circRNA can be a sponge for some proteins, ... through gene sequencing of pancreatic cancer tissue and paired para-carcinoma tissue to establish the hypothesis of the circRNA–miRNA–mRNA interaction network in this disease. The functions of these three types of RNAs were ... billy joe royal - hush
Mechanisms of circRNA/lncRNA-miRNA interactions and …
WebJul 18, 2024 · These findings suggest that in silico reduction of base-pairing interactions between the 3′ end of an IRES and 5′ end of a coding sequence can yield additional … WebApr 13, 2024 · Recent studies have shown that circRNA molecules act as miRNA sponges in cells, thereby relieving the inhibition effect of miRNA on its target genes and increasing the expression level of target genes. This mechanism of action is called the competitive endogenous RNA (ceRNA) mechanism [ 10, 11, 12 ]. WebJan 7, 2024 · The significant function of circRNAs in cancer was recognized in recent work, so a well-organized resource is required for characterizing the interactions between … billy joe royal biography